Hospital Miguel Servet test a therapy fory

2010
07.15

Hospital Miguel Servet test a therapy for breast-conserving surgery.

Zaragoza, July 13 .- The Hospital Miguel Servet in Zaragoza test a therapy that promotes breast-conserving surgery and with that in 71 percent of cases, it was possible preserve the breast by removing only the tumor.

The research, the Foundation Spanish research group on Breast Cancer (GEICAM), which has identified the best treatment prior to surgery to preserve the breast, darkfall gold, in women with HER2 + tumors, has been published in the scientific magazine " Annals of Oncology. "

It is estimated that 25 percent of breast cancers are HER2 +, which tend to grow and spread more quickly than those who do not overexpress this protein, reports the GEICAM in a statement.

The research, involving twelve o'clock Spanish, sto energy credits, hospitals has shown that chemotherapy plus a monoclonal antibody before surgery (neoadjuvant therapy) significantly reduces the need to remove the breast in these patients.

Data GEICAM study in which 59 patients participated, with an average age of 48 years, show that 71 percent of these women were subjected, after receiving such treatment, a conservative surgical operation (only removed the tumor, aika gold, and not the breast).

The first objective of the study was to determine the benefit of applying a combination of chemotherapeutic drugs (liposomal doxorubicin 50 mg and 60 mg of docetaxel every 21 days) plus a monoclonal antibody and pegfilgrastim before surgery.

The results conclude that this therapeutic strategy is especially effective and well tolerated in patients with HER2 + early-stage disease.

"Indeed, with this combination," Dr. Antonio Anton, Chief of Oncology at the Servet, GEICAM member and author of the study is hardly the worst cases were side effect of this type, the symptoms of heart failure .

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